Basic Information
ID: ALA4257002
Type: Binding
Description: Inhibition of recombinant human N-terminal His-FLAG-tagged JARID1B (2 to 751 residues) expressed in baculovirus infected Sf9 cells using H3K4me3-biotin labelled peptide as substrate measured after 30 mins by Lance TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4257002
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.42 | 4.39 | 4.39 |
| 454.46 | 4.88 | 4.88 |
| 400.36 | 3.81 | 3.81 |
| 454.46 | 4.88 | 4.88 |
| 388.33 | 3.94 | 3.94 |
| 384.37 | 4.11 | 4.11 |
| 384.37 | 4.36 | 4.36 |
| 414.39 | 4.00 | 4.00 |
| 452.36 | 5.01 | 5.01 |
| 468.36 | 4.74 | 4.74 |
| 370.34 | 3.80 | 3.80 |
| 418.81 | 4.65 | 4.65 |
| 420.35 | 4.27 | 4.27 |
| 402.36 | 4.24 | 4.24 |
| 402.36 | 4.13 | 4.13 |
| 420.35 | 4.27 | 4.27 |
| 440.47 | 5.29 | 5.29 |
| 388.33 | 4.09 | 4.09 |
| 426.40 | 4.32 | 4.32 |
| 414.37 | 4.42 | 4.42 |
| 467.46 | 4.23 | 4.23 |
| 452.36 | 5.01 | 5.01 |
| 442.42 | 5.01 | 5.01 |
| 442.42 | 5.01 | 5.01 |
| 388.33 | 3.94 | 3.94 |
| 412.42 | 4.55 | 4.55 |
| 404.78 | 4.45 | 4.45 |
| 442.42 | 5.01 | 5.01 |
| 438.33 | 4.41 | 4.41 |
| 384.37 | 4.11 | 4.11 |
| 410.40 | 4.48 | 4.48 |
| 436.80 | 4.78 | 4.78 |
| 404.78 | 4.45 | 4.45 |
| 438.46 | 5.18 | 5.18 |
| 402.36 | 4.13 | 4.13 |
| 418.81 | 4.65 | 4.65 |
| 402.36 | 4.24 | 4.24 |
| 438.46 | 5.18 | 5.18 |
| 406.32 | 4.08 | 4.08 |
| 454.46 | 4.88 | 4.88 |
| 420.35 | 4.27 | 4.27 |
| 406.32 | 4.08 | 4.08 |
| 412.42 | 4.99 | 4.99 |
| 398.39 | 4.30 | 4.30 |
| 438.33 | 4.41 | 4.41 |
| 402.36 | 4.13 | 4.13 |
| 398.39 | 4.75 | 4.75 |
| 467.46 | 4.23 | 4.23 |
| 424.43 | 4.87 | 4.87 |
| 454.46 | 4.88 | 4.88 |
| 420.35 | 4.27 | 4.27 |