Basic Information
ID: ALA4257059
Type: Functional
Description: In-vivo inhibition of CNKSR1 in mouse xenografted with human A549 cells with KRas mutant assessed as inhibition of AKT Ser473 phosphorylation at 75 mg/kg, ip administered as single dose and measured after 1 to 24 hrs post dose
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4257059
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.46 | 2.86 | 2.86 |