Basic Information
ID: ALA4257112
Type: Functional
Description: In vivo inhibition of NHE3 in Sprague-Dawley rat assessed as inhibition of sodium absorption from intestinal lumen by measuring urinary sodium concentration at 1 mg/kg, po via gavage measured after 16 hrs relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4257112
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1217.99 | ||
| 1145.07 | ||
| 1145.07 | ||
| 1205.12 | ||
| 1907.78 | ||
| 1237.98 | ||
| 1777.63 | ||
| 1773.69 | ||
| 1814.69 | ||
| 1832.75 | ||
| 1163.04 | ||
| 1818.73 | ||
| 1788.73 | ||
| 1785.70 | ||
| 1686.57 | ||
| 1728.65 | ||
| 546.52 | 2.86 | 2.86 |
| 1235.58 | ||
| 1315.28 | ||
| 1207.09 | ||
| 1145.07 | ||
| 1731.61 | ||
| 1816.67 | ||
| 1700.59 | ||
| 1786.64 | ||
| 485.36 | 0.95 | 0.95 |
| 1744.65 | ||
| 1815.77 |