Basic Information
ID: ALA4257117
Type: Functional
Description: In vivo inhibition of NHE3 in Sprague-Dawley rat assessed as inhibition of sodium absorption from intestinal lumen by measuring urinary sodium concentration at 3 mg/kg, po via gavage measured after 16 hrs relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4257117
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1145.07 | ||
| 1829.71 | ||
| 1205.12 | ||
| 1907.78 | ||
| 1757.65 | ||
| 1921.80 | ||
| 1815.77 | ||
| 1858.75 | ||
| 1778.69 | ||
| 1777.63 | ||
| 1289.20 | ||
| 1801.65 | ||
| 1548.94 | ||
| 1773.69 | ||
| 1810.67 | ||
| 1743.62 | ||
| 1814.69 | ||
| 1832.75 | ||
| 1163.04 | ||
| 1746.94 | ||
| 1818.73 | ||
| 1334.28 | ||
| 1788.73 | ||
| 1857.86 | ||
| 1218.16 | ||
| 1147.04 | ||
| 1831.68 | ||
| 1785.70 | ||
| 1851.74 | ||
| 1742.67 | ||
| 1491.88 | ||
| 1686.57 | ||
| 1771.67 | ||
| 1859.69 | ||
| 1856.78 | ||
| 1817.70 | ||
| 1827.78 | ||
| 1318.23 | ||
| 1728.65 | ||
| 1903.79 | ||
| 1847.72 | ||
| 1235.58 | ||
| 1844.72 | ||
| 1315.28 | ||
| 1731.61 | ||
| 1179.04 | ||
| 1787.72 | ||
| 1905.85 | ||
| 1808.69 | ||
| 1161.06 | ||
| 1861.71 | ||
| 1887.79 | ||
| 1816.67 | ||
| 1700.59 | ||
| 1994.90 | ||
| 1810.71 | ||
| 1786.64 | ||
| 1277.23 | ||
| 1728.65 | ||
| 1826.75 | ||
| 1744.65 | ||
| 1886.85 | ||
| 1772.66 | ||
| 1815.77 | ||
| 1745.64 |