Assay Report Card

Basic Information

ID: ALA4257120

Type: Functional

Description: In vivo inhibition of NHE3 in Sprague-Dawley rat assessed as urinary potassium concentration at 3 mg/kg, po via gavage measured after 16 hrs relative to control

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1145.07
1829.71
1205.12
1907.78
1757.65
1921.80
1815.77
1858.75
1778.69
1777.63
1289.20
1801.65
1548.94
1773.69
1810.67
1743.62
1814.69
1832.75
1163.04
1746.94
1818.73
1334.28
1788.73
1857.86
1218.16
1147.04
1831.68
1785.70
1851.74
1742.67
1491.88
1686.57
1771.67
1859.69
1856.78
1817.70
1827.78
1318.23
1728.65
1903.79
1847.72
1235.58
1844.72
1315.28
1731.61
1179.04
1787.72
1905.85
1808.69
1161.06
1861.71
1887.79
1816.67
1700.59
1994.90
1810.71
1786.64
1277.23
1728.65
1826.75
1744.65
1886.85
1772.66
1815.77
1745.64