Basic Information
ID: ALA4257141
Type: Binding
Description: Inhibition of rat NHE3 expressed in OK cells assessed as reduction in Na+ dependent H+ antiport co-treated with NaCl-HEPES buffer for 60 mins followed by compound washout and subsequent incubation for 30 mins in presence of NaCl-HEPES buffer by BCECF-AM dye based fluorescence assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4257141
pIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1217.99 | ||
| 1237.98 | ||
| 1217.99 | ||
| 1217.99 | ||
| 485.36 | 0.95 | 0.95 |