Basic Information
ID: ALA4257176
Type: Binding
Description: Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using 21[3H]-17alpha-hydroxyl-pregnenolone as substrate pretreated for 60 mins followed by substrate addition and measured after 4 hrs by Topcount method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4257176
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.55 | 3.22 | 3.22 |
| 440.54 | 3.32 | 3.32 |
| 454.00 | 4.65 | 4.65 |
| 451.57 | 4.53 | 4.53 |
| 457.00 | 3.84 | 3.84 |
| 437.54 | 4.14 | 4.14 |
| 404.49 | 3.26 | 3.26 |
| 444.97 | 5.08 | 5.08 |
| 463.58 | 4.67 | 4.67 |
| 509.04 | 3.99 | 3.99 |
| 482.05 | 5.43 | 5.43 |
| 468.60 | 4.10 | 4.10 |
| 483.04 | 4.37 | 4.37 |
| 417.94 | 5.24 | 5.24 |
| 465.59 | 4.92 | 4.92 |
| 445.54 | 4.14 | 4.14 |
| 420.95 | 3.77 | 3.77 |
| 401.49 | 4.07 | 4.07 |
| 491.51 | 5.03 | 5.03 |
| 471.03 | 4.23 | 4.23 |
| 520.06 | 4.66 | 4.66 |
| 480.03 | 5.19 | 5.19 |
| 447.97 | 4.26 | 4.26 |
| 431.52 | 3.75 | 3.75 |
| 428.51 | 4.57 | 4.57 |
| 420.94 | 4.42 | 4.42 |
| 401.49 | 4.73 | 4.73 |
| 417.94 | 4.59 | 4.59 |
| 485.05 | 4.62 | 4.62 |
| 433.00 | 5.29 | 5.29 |
| 494.04 | 5.95 | 5.95 |
| 403.50 | 4.34 | 4.34 |
| 493.53 | 4.64 | 4.64 |
| 446.98 | 4.81 | 4.81 |
| 388.47 | 3.42 | 3.42 |
| 422.96 | 7.81 | 7.81 |
| 431.97 | 5.16 | 5.16 |
| 402.50 | 3.48 | 3.48 |
| 490.05 | 5.47 | 5.47 |
| 472.03 | 6.42 | 6.42 |
| 508.03 | 5.59 | 5.59 |
| 488.56 | 4.45 | 4.45 |
| 352.41 | 6.12 | 6.12 |
| 354.22 | 5.82 | 5.82 |
| 522.05 | 4.59 | 4.59 |
| 401.49 | 4.73 | 4.73 |
| 453.58 | 4.14 | 4.14 |
| 519.50 | 4.84 | 4.84 |
| 413.54 | 5.59 | 5.59 |
| 417.94 | 5.24 | 5.24 |
| 564.07 | 5.17 | 5.17 |
| 500.60 | 4.96 | 4.96 |
| 490.58 | 4.07 | 4.07 |
| 603.07 | 6.16 | 6.16 |
| 354.43 | 5.73 | 5.73 |
| 447.97 | 5.15 | 5.15 |
| 467.61 | 4.53 | 4.53 |
| 465.59 | 4.29 | 4.29 |
| 508.02 | 4.15 | 4.15 |
| 341.21 | 4.51 | 4.51 |
| 544.08 | 5.14 | 5.14 |
| 598.51 | 5.83 | 5.83 |
| 528.01 | 5.63 | 5.63 |
| 484.00 | 5.11 | 5.11 |