Basic Information
ID: ALA4257191
Type: Binding
Description: Inhibition of recombinant CYP11 (unknown origin) expressed in human AD293 cells assessed as reduction in cortisol level preincubated for 60 mins followed by 11-deoxy cortisol substrate addition and measured after 12 hrs by LC-MS method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4257191
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 598.10 | 3.42 | 3.42 |
| 571.07 | 3.93 | 3.93 |
| 461.95 | 5.08 | 5.08 |
| 668.60 | 5.06 | 5.06 |
| 547.08 | 3.10 | 3.10 |
| 540.06 | 3.83 | 3.83 |
| 511.02 | 3.69 | 3.69 |
| 598.10 | 3.42 | 3.42 |
| 644.58 | 4.58 | 4.58 |
| 607.56 | 4.29 | 4.29 |
| 727.59 | 6.08 | 6.08 |
| 644.02 | 4.76 | 4.76 |
| 547.08 | 3.10 | 3.10 |
| 609.58 | 4.54 | 4.54 |
| 633.56 | 3.91 | 3.91 |
| 545.47 | 4.34 | 4.34 |
| 545.47 | 4.34 | 4.34 |
| 496.39 | 5.74 | 5.74 |
| 595.55 | 4.15 | 4.15 |