Basic Information
ID: ALA4257284
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged JMJD2A (1 to 350 residues) expressed in Escherichia coli using H3K9me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4257284
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 203.20 | 1.18 | 1.18 |
| 227.23 | 0.66 | 0.66 |
| 337.77 | 2.83 | 2.83 |
| 305.34 | 2.98 | 2.98 |
| 324.39 | 1.50 | 1.50 |
| 350.42 | 3.08 | 3.08 |
| 361.32 | 3.90 | 3.90 |
| 304.35 | 1.22 | 1.22 |
| 350.42 | 3.08 | 3.08 |
| 323.35 | 2.89 | 2.89 |
| 357.42 | 3.25 | 3.25 |
| 355.83 | 4.27 | 4.27 |
| 297.29 | 2.83 | 2.83 |
| 367.42 | 3.52 | 3.52 |
| 327.77 | 3.54 | 3.54 |
| 297.29 | 2.83 | 2.83 |
| 354.38 | 2.91 | 2.91 |
| 310.37 | 1.22 | 1.22 |
| 307.35 | 3.19 | 3.19 |
| 404.39 | 3.79 | 3.79 |
| 297.29 | 2.99 | 2.99 |
| 351.80 | 3.02 | 3.02 |
| 293.33 | 3.25 | 3.25 |
| 385.35 | 3.39 | 3.39 |
| 321.38 | 3.89 | 3.89 |
| 356.81 | 3.43 | 3.43 |
| 391.41 | 3.26 | 3.26 |
| 323.33 | 3.32 | 3.32 |
| 322.37 | 2.78 | 2.78 |
| 333.39 | 3.76 | 3.76 |
| 300.36 | 1.99 | 1.99 |
| 331.38 | 3.12 | 3.12 |
| 300.36 | 1.99 | 1.99 |
| 380.42 | 3.45 | 3.45 |
| 345.41 | 3.37 | 3.37 |
| 348.41 | 3.10 | 3.10 |
| 368.41 | 3.30 | 3.30 |
| 405.77 | 3.85 | 3.85 |
| 300.32 | 1.27 | 1.27 |
| 382.85 | 3.75 | 3.75 |
| 307.35 | 3.64 | 3.64 |
| 355.40 | 4.36 | 4.36 |
| 367.38 | 3.78 | 3.78 |
| 366.40 | 3.24 | 3.24 |
| 354.39 | 2.91 | 2.91 |
| 343.39 | 4.04 | 4.04 |
| 352.37 | 2.85 | 2.85 |
| 286.34 | 1.74 | 1.74 |
| 323.33 | 3.32 | 3.32 |