Basic Information
ID: ALA4257286
Type: Binding
Description: Inhibition of KDM5A/KDM5B in human ZR-75-1 cells assessed as increase in H3K4me3 level after 72 hrs by fluorometric immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4257286
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 203.20 | 1.18 | 1.18 |
| 309.33 | 2.86 | 2.86 |
| 349.39 | 3.64 | 3.64 |
| 227.23 | 0.66 | 0.66 |
| 311.32 | 3.03 | 3.03 |
| 348.41 | 3.45 | 3.45 |
| 305.34 | 2.98 | 2.98 |
| 260.30 | 1.20 | 1.20 |
| 297.29 | 2.83 | 2.83 |
| 313.74 | 3.50 | 3.50 |
| 361.32 | 3.90 | 3.90 |
| 364.40 | 3.06 | 3.06 |
| 323.35 | 2.89 | 2.89 |
| 313.74 | 3.50 | 3.50 |
| 355.83 | 4.27 | 4.27 |
| 297.29 | 2.83 | 2.83 |
| 327.77 | 3.54 | 3.54 |
| 297.29 | 2.83 | 2.83 |
| 231.25 | 2.05 | 2.05 |
| 307.35 | 3.19 | 3.19 |
| 297.29 | 2.99 | 2.99 |
| 319.36 | 3.72 | 3.72 |
| 318.34 | 3.33 | 3.33 |
| 293.33 | 3.25 | 3.25 |
| 331.73 | 3.64 | 3.64 |
| 345.36 | 3.03 | 3.03 |
| 359.79 | 4.51 | 4.51 |
| 380.42 | 3.45 | 3.45 |
| 348.41 | 3.10 | 3.10 |
| 307.35 | 3.45 | 3.45 |
| 311.32 | 3.03 | 3.03 |
| 279.30 | 2.69 | 2.69 |
| 309.32 | 2.86 | 2.86 |
| 286.34 | 1.74 | 1.74 |