Basic Information
ID: ALA4257968
Type: ADME
Description: Inhibition of recombinant human CYP3A4 expressed in baker's yeast-derived microsomes (Sacchrosomes) at 10 uM using dibenzylfluorescein substrate by EROD assay relative to control
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4257968
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 190.15 | 1.03 | 1.03 |
| 216.19 | 2.55 | 2.55 |
| 272.30 | 4.61 | 4.61 |
| 188.18 | 1.72 | 1.72 |
| 260.24 | 2.86 | 2.86 |
| 289.14 | 2.97 | 2.97 |
| 246.22 | 2.56 | 2.56 |
| 358.35 | 3.20 | 3.20 |
| 300.31 | 3.89 | 3.89 |
| 292.29 | 4.21 | 4.21 |
| 294.31 | 3.90 | 3.90 |
| 379.41 | 4.35 | 4.35 |