Basic Information
ID: ALA4257976
Type: ADME
Description: Inhibition of human recombinant CYP2C9 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin substrate substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by fluorescence assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4257976
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 190.15 | 1.03 | 1.03 |
| 216.19 | 2.55 | 2.55 |
| 188.18 | 1.72 | 1.72 |
| 260.24 | 2.86 | 2.86 |
| 289.14 | 2.97 | 2.97 |
| 246.22 | 2.56 | 2.56 |
| 358.35 | 3.20 | 3.20 |
| 300.31 | 3.89 | 3.89 |
| 292.29 | 4.21 | 4.21 |
| 294.31 | 3.90 | 3.90 |
| 379.41 | 4.35 | 4.35 |