Basic Information
ID: ALA4257978
Type: ADME
Description: Inhibition of human recombinant CYP3A4 expressed in HEK293 cells using dibenzylfluorescein substrate substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by fluorescence assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4257978
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 190.15 | 1.03 | 1.03 |
| 216.19 | 2.55 | 2.55 |
| 188.18 | 1.72 | 1.72 |
| 260.24 | 2.86 | 2.86 |
| 289.14 | 2.97 | 2.97 |
| 246.22 | 2.56 | 2.56 |
| 358.35 | 3.20 | 3.20 |
| 300.31 | 3.89 | 3.89 |
| 292.29 | 4.21 | 4.21 |
| 294.31 | 3.90 | 3.90 |
| 379.41 | 4.35 | 4.35 |