Basic Information
ID: ALA4258719
Type: Binding
Description: Binding affinity to recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli assessed as inhibition of interaction with Abl by measuring Abl-mediated CRK-2 phosphorylation at Y221 residue at 1 uM after 10 to 30 mins by PAGE analysis (Rvb = 62%)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4258719
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.62 | 4.59 | 4.59 |
| 1683.99 |