Basic Information
ID: ALA4258945
Type: ADME
Description: Inhibition of sheep COX1 at 10 uM assessed as reduction in PGE2 formation using arachidonic acid as substrate by enzyme immunoassay relative to control
Organism: Ovis aries
Activity Charts
Bioactivity
Activity Types for Assay ALA4258945
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 395.47 | 3.70 | 3.70 |
| 473.56 | 3.10 | 3.10 |
| 398.47 | 3.27 | 3.27 |
| 381.44 | 3.66 | 3.66 |
| 473.56 | 3.10 | 3.10 |
| 490.59 | 3.06 | 3.06 |
| 476.56 | 2.75 | 2.75 |
| 381.44 | 3.66 | 3.66 |
| 459.53 | 3.06 | 3.06 |
| 395.47 | 3.70 | 3.70 |
| 395.47 | 3.70 | 3.70 |
| 476.56 | 2.67 | 2.67 |
| 395.47 | 3.70 | 3.70 |
| 381.44 | 3.66 | 3.66 |
| 398.47 | 3.35 | 3.35 |
| 459.53 | 3.06 | 3.06 |
| 381.44 | 3.66 | 3.66 |
| 490.59 | 3.06 | 3.06 |
| 473.56 | 3.10 | 3.10 |
| 476.56 | 2.67 | 2.67 |
| 395.47 | 3.70 | 3.70 |
| 459.53 | 3.06 | 3.06 |
| 395.47 | 3.70 | 3.70 |
| 459.53 | 3.06 | 3.06 |
| 459.53 | 3.06 | 3.06 |
| 412.50 | 3.66 | 3.66 |
| 476.56 | 2.75 | 2.75 |