Basic Information
ID: ALA4259040
Type: Binding
Description: Inhibition of recombinant human full-length N-terminal GST-fused/His6-tagged IKKepsilon (M1 to V716 residues) expressed in Sf9 insect cells using ERLLDDRHDSGLDSMKDEE peptide as substrate measured after 60 mins by ADP-Glo kinase assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4259040
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 173.22 | 1.97 | 1.97 |
| 207.66 | 2.62 | 2.62 |
| 366.42 | 2.35 | 2.35 |
| 284.15 | 3.41 | 3.41 |
| 284.15 | 3.41 | 3.41 |
| 313.19 | 3.33 | 3.33 |
| 275.74 | 3.14 | 3.14 |
| 312.20 | 4.19 | 4.19 |
| 201.27 | 2.58 | 2.58 |
| 243.31 | 2.72 | 2.72 |
| 347.21 | 4.34 | 4.34 |
| 242.11 | 3.27 | 3.27 |
| 187.25 | 2.28 | 2.28 |
| 257.21 | 2.87 | 2.87 |
| 347.21 | 3.83 | 3.83 |
| 338.12 | 4.19 | 4.19 |
| 324.21 | 4.19 | 4.19 |
| 242.11 | 3.27 | 3.27 |
| 249.70 | 2.75 | 2.75 |
| 256.14 | 3.28 | 3.28 |
| 324.21 | 4.19 | 4.19 |
| 298.17 | 3.80 | 3.80 |
| 252.12 | 2.73 | 2.73 |
| 342.23 | 4.53 | 4.53 |
| 187.25 | 2.28 | 2.28 |
| 346.22 | 4.44 | 4.44 |
| 279.34 | 3.55 | 3.55 |
| 322.76 | 4.02 | 4.02 |
| 352.27 | 4.97 | 4.97 |
| 249.70 | 2.75 | 2.75 |
| 218.05 | 1.20 | 1.20 |
| 310.18 | 3.80 | 3.80 |
| 223.28 | 3.12 | 3.12 |
| 217.23 | 1.70 | 1.70 |
| 347.21 | 3.83 | 3.83 |
| 298.17 | 3.66 | 3.66 |
| 256.14 | 3.28 | 3.28 |
| 338.24 | 4.58 | 4.58 |
| 309.21 | 4.00 | 4.00 |
| 347.21 | 3.83 | 3.83 |
| 207.66 | 2.62 | 2.62 |
| 241.22 | 2.99 | 2.99 |
| 252.12 | 2.73 | 2.73 |
| 283.25 | 3.12 | 3.12 |
| 218.05 | 1.20 | 1.20 |