Assay Report Card

Basic Information

ID: ALA4259295

Type: Binding

Description: Inhibition of PKCzeta in human U937 cells assessed as reduction in TNFalpha-induced NFkappaB activation at 10 uM preincubated for 3 hrs followed by TNFalpha-stimulation and measured after 2.5 hrs by bright-glo luciferase reporter gene assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
399.285.765.76