Basic Information
ID: ALA4259296
Type: Binding
Description: Inhibition of PKCzeta in human U937 cells assessed as reduction in TNFalpha-induced NFkappaB activation preincubated for 3 hrs followed by TNFalpha-stimulation and measured after 2.5 hrs by bright-glo luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Protein kinase C zeta(ALA3438)
Document: ALA4257514
Inhibition of PKCzeta in human U937 cells assessed as reduction in TNFalpha-induced NFkappaB activation preincubated for 3 hrs followed by TNFalpha-stimulation and measured after 2.5 hrs by bright-glo luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4259296
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.28 | 5.76 | 5.76 |