Assay Report Card

Basic Information

ID: ALA4259315

Type: ADME

Description: Efflux ratio of permeability across basolateral to apical over apical to basolateral side in MDCK cells expressing MDR1 at 0.5 uM after 60 mins by LC-MS/MS analysis

Organism: Canis lupus familiaris

Cell type: MDCK

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
411.482.852.85
394.482.102.10
409.491.811.81
409.491.811.81
395.471.501.50
423.521.821.82
359.472.162.16
429.472.932.93
427.481.891.89
427.481.891.89
412.472.182.18
441.511.901.90
377.462.242.24
413.461.581.58
423.521.821.82
441.511.901.90