Basic Information
ID: ALA4260511
Type: Binding
Description: Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by fluorescence based FDSS assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Voltage-gated N-type calcium channel alpha-1B subunit(ALA4478)
Document: ALA4257570
Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by fluorescence based FDSS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4260511
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.00 | 6.71 | 6.71 |
| 396.92 | 5.87 | 5.87 |
| 424.97 | 6.65 | 6.65 |
| 425.96 | 6.05 | 6.05 |
| 434.58 | 6.40 | 6.40 |
| 435.57 | 5.79 | 5.79 |
| 395.93 | 6.04 | 6.04 |
| 410.95 | 6.12 | 6.12 |
| 410.95 | 6.12 | 6.12 |
| 466.07 | 7.49 | 7.49 |
| 396.92 | 5.87 | 5.87 |
| 396.92 | 5.87 | 5.87 |
| 395.93 | 6.04 | 6.04 |
| 2639.19 | ||
| 415.54 | 5.87 | 5.87 |
| 368.86 | 5.10 | 5.10 |
| 422.96 | 6.56 | 6.56 |
| 405.54 | 5.70 | 5.70 |