Basic Information
ID: ALA4260547
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4260547
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.75 | 2.77 | 2.77 |
| 341.74 | 2.91 | 2.91 |
| 278.31 | 3.55 | 3.55 |
| 302.34 | 3.03 | 3.03 |
| 303.33 | 2.42 | 2.42 |
| 330.40 | 3.59 | 3.59 |
| 321.32 | 2.56 | 2.56 |
| 334.36 | 3.42 | 3.42 |
| 322.76 | 3.37 | 3.37 |
| 288.31 | 2.72 | 2.72 |
| 316.37 | 3.28 | 3.28 |
| 302.34 | 3.03 | 3.03 |
| 336.79 | 3.68 | 3.68 |