Assay Report Card

Basic Information

ID: ALA4261078

Type: ADME

Description: Hepatic clearance in Sprague-Dawley rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Liver

Subcellular Fraction: microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
547.576.726.72
620.397.167.16
540.366.366.36
565.566.866.86
564.027.237.23
546.037.097.09
624.126.506.50
565.016.636.63
565.016.636.63
551.067.097.09