Basic Information
ID: ALA4261237
Type: Binding
Description: Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4261237
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.26 | -3.07 | -3.07 |
| 394.38 | -1.63 | -1.63 |
| 332.27 | -2.78 | -2.78 |
| 319.31 | -2.43 | -2.43 |
| 374.39 | -1.75 | -1.75 |
| 451.43 | -1.67 | -1.67 |
| 452.40 | -1.99 | -1.99 |
| 550.57 | -1.38 | -1.38 |
| 348.35 | -2.96 | -2.96 |
| 388.42 | -2.16 | -2.16 |
| 305.28 | -2.68 | -2.68 |
| 449.42 | -2.55 | -2.55 |
| 451.43 | -1.67 | -1.67 |
| 374.39 | -1.75 | -1.75 |
| 374.39 | -1.90 | -1.90 |
| 448.43 | -1.82 | -1.82 |
| 331.32 | -2.29 | -2.29 |
| 333.34 | -1.90 | -1.90 |
| 402.44 | -0.97 | -0.97 |
| 416.47 | -0.58 | -0.58 |
| 347.36 | -1.65 | -1.65 |
| 428.44 | -2.06 | -2.06 |
| 412.44 | -1.03 | -1.03 |
| 402.44 | -0.97 | -0.97 |
| 402.44 | -0.97 | -0.97 |
| 409.40 | -2.05 | -2.05 |
| 502.40 | -1.11 | -1.11 |
| 319.31 | -2.29 | -2.29 |
| 360.36 | -2.14 | -2.14 |
| 361.39 | -1.12 | -1.12 |
| 388.42 | -1.36 | -1.36 |
| 409.40 | -2.05 | -2.05 |
| 353.33 | -1.77 | -1.77 |
| 360.36 | -2.29 | -2.29 |
| 444.53 | 0.20 | 0.20 |
| 464.43 | -2.12 | -2.12 |
| 317.29 | -2.68 | -2.68 |
| 347.36 | -1.51 | -1.51 |
| 491.46 | -2.17 | -2.17 |
| 478.41 | -2.43 | -2.43 |
| 477.47 | -2.06 | -2.06 |
| 416.47 | -0.58 | -0.58 |
| 388.42 | -1.36 | -1.36 |
| 388.42 | -1.51 | -1.51 |
| 388.42 | -1.36 | -1.36 |
| 333.34 | -2.04 | -2.04 |