Basic Information
ID: ALA4262904
Type: Binding
Description: Inhibition of B-Raf V600E mutant (unknown origin) using fluorescein-MAP2K1 as substrate after 1 hr by electrophoretic assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4262904
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.24 | 1.99 | 1.99 |
| 318.24 | 1.69 | 1.69 |
| 520.95 | 5.01 | 5.01 |
| 489.93 | 5.54 | 5.54 |
| 667.74 | 6.58 | 6.58 |
| 425.42 | 2.65 | 2.65 |
| 394.40 | 3.25 | 3.25 |
| 410.86 | 3.76 | 3.76 |
| 390.44 | 3.41 | 3.41 |
| 473.30 | 4.01 | 4.01 |
| 408.43 | 3.55 | 3.55 |
| 370.38 | 2.35 | 2.35 |
| 362.40 | 4.33 | 4.33 |
| 363.39 | 3.73 | 3.73 |
| 363.39 | 3.73 | 3.73 |
| 442.29 | 4.49 | 4.49 |
| 393.42 | 3.03 | 3.03 |
| 483.54 | 4.74 | 4.74 |
| 377.42 | 3.91 | 3.91 |
| 378.40 | 3.31 | 3.31 |
| 356.45 | 3.34 | 3.34 |
| 409.42 | 2.01 | 2.01 |
| 423.45 | 2.47 | 2.47 |
| 463.51 | 3.25 | 3.25 |
| 453.47 | 1.83 | 1.83 |
| 467.50 | 2.22 | 2.22 |
| 493.54 | 3.02 | 3.02 |
| 485.52 | 4.17 | 4.17 |
| 486.50 | 3.56 | 3.56 |
| 489.51 | 2.90 | 2.90 |
| 519.57 | 5.36 | 5.36 |
| 386.38 | 2.13 | 2.13 |
| 400.41 | 2.59 | 2.59 |
| 400.41 | 2.16 | 2.16 |
| 411.39 | 2.43 | 2.43 |
| 441.42 | 2.44 | 2.44 |
| 421.43 | 2.89 | 2.89 |
| 437.88 | 3.41 | 3.41 |
| 437.88 | 3.41 | 3.41 |
| 455.87 | 3.36 | 3.36 |
| 427.46 | 2.96 | 2.96 |
| 443.91 | 3.47 | 3.47 |
| 443.91 | 3.47 | 3.47 |
| 461.90 | 3.42 | 3.42 |
| 399.45 | 3.81 | 3.81 |
| 413.48 | 4.12 | 4.12 |
| 429.48 | 3.82 | 3.82 |
| 413.48 | 4.12 | 4.12 |
| 433.90 | 4.47 | 4.47 |
| 398.47 | 4.42 | 4.42 |
| 399.45 | 3.81 | 3.81 |
| 429.48 | 3.82 | 3.82 |
| 417.44 | 3.95 | 3.95 |
| 400.44 | 3.21 | 3.21 |
| 399.45 | 3.81 | 3.81 |
| 413.48 | 4.12 | 4.12 |
| 417.44 | 3.95 | 3.95 |
| 412.50 | 3.73 | 3.73 |
| 452.56 | 4.65 | 4.65 |
| 438.54 | 4.26 | 4.26 |
| 385.47 | 4.17 | 4.17 |
| 399.50 | 4.51 | 4.51 |
| 411.51 | 4.91 | 4.91 |
| 413.48 | 4.43 | 4.43 |
| 372.43 | 4.46 | 4.46 |
| 399.45 | 4.41 | 4.41 |
| 369.43 | 4.42 | 4.42 |
| 355.40 | 4.39 | 4.39 |
| 385.47 | 4.52 | 4.52 |
| 427.51 | 4.65 | 4.65 |
| 427.51 | 4.65 | 4.65 |
| 383.46 | 4.63 | 4.63 |
| 452.56 | 4.75 | 4.75 |
| 496.62 | 4.46 | 4.46 |
| 452.56 | 4.61 | 4.61 |
| 452.56 | 4.61 | 4.61 |
| 438.54 | 4.36 | 4.36 |
| 435.53 | 5.72 | 5.72 |
| 421.50 | 5.33 | 5.33 |
| 436.52 | 4.49 | 4.49 |
| 436.52 | 4.14 | 4.14 |
| 413.48 | 4.64 | 4.64 |
| 417.90 | 5.29 | 5.29 |
| 417.90 | 5.29 | 5.29 |
| 397.48 | 4.94 | 4.94 |
| 397.48 | 4.94 | 4.94 |
| 487.56 | 5.05 | 5.05 |
| 501.58 | 5.23 | 5.23 |
| 526.62 | 4.23 | 4.23 |
| 554.72 | 5.69 | 5.69 |
| 593.70 | 4.93 | 4.93 |
| 611.69 | 5.07 | 5.07 |
| 466.59 | 5.10 | 5.10 |
| 437.47 | 3.31 | 3.31 |
| 440.88 | 3.77 | 3.77 |
| 391.43 | 2.81 | 2.81 |
| 424.43 | 3.25 | 3.25 |