Basic Information
ID: ALA4262999
Type: Binding
Description: Inhibition of human MPO assessed as reduction in enzyme-mediated chlorination by measuring reduction in HOCl formation at 10 uM preincubated for 10 mins followed by H2O2/NaCl addition and measured at 30 secs time interval for 5 mins by APF dye based fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4262999
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.35 | 2.78 | 2.78 |
| 242.24 | 0.91 | 0.91 |
| 252.30 | 0.96 | 0.96 |
| 289.55 | 4.42 | 4.42 |