Basic Information
ID: ALA4263001
Type: Binding
Description: Inhibition of human MPO assessed as reduction in enzyme-mediated chlorination by measuring reduction in HOCl formation preincubated for 10 mins followed by H2O2/NaCl addition and measured at 30 secs time interval for 5 mins by APF dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4263001
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.35 | 2.78 | 2.78 |
| 242.24 | 0.91 | 0.91 |
| 257.25 | 1.22 | 1.22 |
| 241.25 | 1.51 | 1.51 |
| 272.27 | 0.92 | 0.92 |
| 252.30 | 0.96 | 0.96 |
| 270.30 | 1.76 | 1.76 |
| 256.27 | 0.95 | 0.95 |
| 260.23 | 1.05 | 1.05 |
| 243.23 | 1.03 | 1.03 |
| 289.55 | 4.42 | 4.42 |
| 241.25 | 1.51 | 1.51 |
| 256.27 | 1.22 | 1.22 |
| 256.27 | 1.22 | 1.22 |
| 276.69 | 1.56 | 1.56 |
| 228.22 | 1.12 | 1.12 |
| 276.69 | 1.56 | 1.56 |
| 227.23 | 1.33 | 1.33 |
| 308.25 | 1.51 | 1.51 |
| 260.23 | 1.05 | 1.05 |
| 260.23 | 1.05 | 1.05 |
| 256.27 | 0.92 | 0.92 |
| 310.24 | 1.93 | 1.93 |