Basic Information
ID: ALA4263011
Type: Binding
Description: Inhibition of mouse C-terminal His10 tagged MPO (Met16 to Thr718 residues) assessed as reduction in enzyme-mediated chlorination by measuring reduction in HOCl formation preincubated for 10 mins followed by H2O2/NaCl addition and measured at 30 secs time interval for 5 mins by APF dye based fluorescence assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4263011
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 242.24 | 0.91 | 0.91 |
| 289.55 | 4.42 | 4.42 |