Basic Information
ID: ALA4263113
Type: Functional
Description: Antagonist activity at N-terminal FLAG-tagged human full-length GnRHR expressed in HEK293T cells assessed as inhibition of GnRH-induced calcium mobilization preincubated for 15 mins followed by agonist addition by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4263113
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 657.78 | 7.85 | 7.85 |
| 476.63 | 5.79 | 5.79 |
| 491.63 | 6.81 | 6.81 |
| 509.63 | 5.57 | 5.57 |
| 577.69 | 1.41 | 1.41 |
| 380.51 | 4.62 | 4.62 |
| 639.76 | 3.12 | 3.12 |
| 461.59 | 4.41 | 4.41 |
| 531.67 | 5.31 | 5.31 |
| 744.85 | 3.27 | 3.27 |
| 618.74 | 1.56 | 1.56 |
| 372.52 | 4.28 | 4.28 |
| 602.74 | 4.42 | 4.42 |