Basic Information
ID: ALA4263518
Type: Binding
Description: Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured after 60 secs
Organism: Leishmania major
Activity Charts
Bioactivity
Activity Types for Assay ALA4263518
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 146.14 | 1.79 | 1.79 |
| 282.34 | 2.39 | 2.39 |
| 180.16 | 1.20 | 1.20 |
| 148.16 | 1.78 | 1.78 |
| 286.24 | 2.28 | 2.28 |
| 194.19 | 1.50 | 1.50 |
| 154.12 | 0.80 | 0.80 |
| 480.65 | 4.94 | 4.94 |
| 162.14 | 1.50 | 1.50 |
| 164.16 | 1.49 | 1.49 |
| 318.24 | 1.69 | 1.69 |
| 270.24 | 2.58 | 2.58 |
| 290.27 | 1.55 | 1.55 |
| 344.32 | 2.90 | 2.90 |
| 516.46 | 1.03 | 1.03 |
| 346.38 | 1.49 | 1.49 |
| 374.39 | 1.53 | 1.53 |
| 358.39 | 2.04 | 2.04 |
| 358.39 | 2.55 | 2.55 |
| 346.38 | 1.49 | 1.49 |
| 360.36 | 1.14 | 1.14 |
| 610.52 | -1.69 | -1.69 |
| 316.27 | 2.29 | 2.29 |
| 516.46 | 1.03 | 1.03 |
| 354.31 | -0.65 | -0.65 |
| 464.38 | -0.54 | -0.54 |
| 378.42 | 0.95 | 0.95 |
| 432.38 | 0.05 | 0.05 |
| 328.32 | 3.19 | 3.19 |
| 348.40 | 1.88 | 1.88 |
| 364.39 | 1.09 | 1.09 |
| 368.43 | 1.31 | 1.31 |
| 1131.27 | ||
| 302.46 | 5.04 | 5.04 |
| 374.39 | 1.53 | 1.53 |
| 303.36 | 0.92 | 0.92 |
| 344.36 | 2.16 | 2.16 |
| 414.72 | 8.02 | 8.02 |
| 438.43 | 0.94 | 0.94 |
| 342.39 | 2.83 | 2.83 |
| 312.27 | -0.15 | -0.15 |
| 302.46 | 5.21 | 5.21 |
| 316.44 | 5.08 | 5.08 |
| 360.41 | 2.19 | 2.19 |
| 450.44 | 0.77 | 0.77 |
| 334.46 | 4.66 | 4.66 |
| 346.38 | 2.24 | 2.24 |
| 448.60 | 6.28 | 6.28 |
| 594.52 | -1.27 | -1.27 |
| 378.42 | 1.23 | 1.23 |
| 516.46 | 1.03 | 1.03 |
| 348.48 | 4.59 | 4.59 |
| 360.41 | 2.18 | 2.18 |
| 420.46 | 1.80 | 1.80 |
| 304.35 | 0.85 | 0.85 |
| 272.48 | 6.14 | 6.14 |