Basic Information
ID: ALA4264792
Type: Binding
Description: Transrepression of RORgammat in anti-CD3/CD28 stimulated human PBMC derived CD4-positive T cells assessed as suppression of T cell differentiation to Th17 cells by measuring reduction in IL-17A level after 7 days by flow cytometry analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Nuclear receptor ROR-gamma(ALA1741186)
Document: ALA4261613
Transrepression of RORgammat in anti-CD3/CD28 stimulated human PBMC derived CD4-positive T cells assessed as suppression of T cell differentiation to Th17 cells by measuring reduction in IL-17A level after 7 days by flow cytometry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4264792
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.59 | 4.58 | 4.58 |
| 508.58 | 3.98 | 3.98 |
| 482.58 | 4.72 | 4.72 |
| 478.61 | 4.89 | 4.89 |
| 482.58 | 4.72 | 4.72 |
| 518.56 | 5.00 | 5.00 |
| 482.58 | 4.72 | 4.72 |
| 500.57 | 4.86 | 4.86 |
| 500.57 | 4.86 | 4.86 |