Assay Report Card

Basic Information

ID: ALA4264838

Type: Binding

Description: Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system assessed as fraction of unbound kinase to substrate at 10 uM after 1 hr by KinomeScan assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
459.414.434.43
501.495.565.56
538.315.195.19
473.444.744.74