Assay Report Card

Basic Information

ID: ALA4265026

Type: Binding

Description: Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxymethyl-4-methylumbelliferone as substrate measured at 5 min intervals over 60 mins in presence of CoCl2 by fluorescence assay

Organism: Streptococcus pneumoniae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
311.33-0.85-0.85
452.442.312.31
362.320.090.09
336.350.460.46
437.510.770.77
452.442.312.31
327.40-0.05-0.05
310.35-0.89-0.89
347.39-1.45-1.45