Basic Information
ID: ALA4265037
Type: Binding
Description: Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using compound pre-incubated with 1Eq DTT and using acetoxymethyl-4-methylumbelliferone as substrate measured at 2 min intervals over 10 mins in presence of ZnCl2 by fluorescence assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4265037
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.46 | -0.50 | -0.50 |
| 343.47 | 0.89 | 0.89 |
| 327.40 | 0.08 | 0.08 |