Assay Report Card

Basic Information

ID: ALA4265039

Type: Binding

Description: Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compound pre-incubated with 1Eq DTT and using acetoxymethyl-4-methylumbelliferone as substrate measured at 5 min intervals over 60 mins in presence of ZnCl2 by fluorescence assay

Organism: Streptococcus pneumoniae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
363.46-0.50-0.50
343.470.890.89
327.400.080.08