Basic Information
ID: ALA4265322
Type: Binding
Description: Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4265322
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.73 | 7.55 | 7.55 |
| 314.37 | 2.12 | 2.12 |
| 325.39 | 0.50 | 0.50 |
| 406.49 | 1.04 | 1.04 |
| 352.37 | 1.80 | 1.80 |
| 388.45 | 0.93 | 0.93 |
| 309.35 | 0.06 | 0.06 |
| 405.44 | -0.90 | -0.90 |
| 362.41 | 0.54 | 0.54 |
| 403.46 | 0.31 | 0.31 |
| 348.38 | 0.05 | 0.05 |
| 417.46 | 1.72 | 1.72 |
| 405.52 | 2.11 | 2.11 |
| 389.44 | 0.30 | 0.30 |
| 400.46 | 0.97 | 0.97 |
| 400.46 | 0.97 | 0.97 |
| 443.53 | 1.19 | 1.19 |
| 417.49 | 0.80 | 0.80 |
| 341.39 | 2.15 | 2.15 |
| 405.44 | 0.27 | 0.27 |
| 358.38 | 0.62 | 0.62 |
| 421.50 | 0.74 | 0.74 |
| 442.50 | 0.61 | 0.61 |
| 407.48 | 0.43 | 0.43 |
| 325.39 | 0.31 | 0.31 |
| 347.40 | 0.16 | 0.16 |
| 404.45 | 0.88 | 0.88 |
| 301.32 | 1.37 | 1.37 |
| 406.49 | 1.04 | 1.04 |
| 403.46 | 0.61 | 0.61 |
| 380.47 | 0.09 | 0.09 |
| 406.49 | 1.04 | 1.04 |
| 417.46 | 1.72 | 1.72 |
| 403.46 | 0.31 | 0.31 |
| 404.45 | -0.29 | -0.29 |
| 405.50 | 1.64 | 1.64 |
| 429.50 | 1.59 | 1.59 |
| 417.49 | 0.80 | 0.80 |
| 351.43 | 1.03 | 1.03 |
| 514.63 | 1.90 | 1.90 |
| 418.48 | 1.36 | 1.36 |
| 427.48 | 1.41 | 1.41 |
| 405.52 | 2.11 | 2.11 |
| 403.46 | 0.31 | 0.31 |
| 379.44 | 0.18 | 0.18 |
| 428.47 | 0.30 | 0.30 |
| 434.54 | 1.65 | 1.65 |
| 345.38 | 1.39 | 1.39 |
| 460.51 | 0.99 | 0.99 |
| 341.39 | 2.29 | 2.29 |
| 308.40 | 1.92 | 1.92 |
| 337.40 | 0.55 | 0.55 |
| 390.42 | 0.57 | 0.57 |
| 434.54 | 1.65 | 1.65 |
| 429.50 | 1.59 | 1.59 |
| 363.44 | 0.94 | 0.94 |
| 347.40 | 0.16 | 0.16 |
| 459.53 | 0.42 | 0.42 |
| 444.51 | 1.75 | 1.75 |
| 404.45 | 0.88 | 0.88 |
| 400.46 | 0.97 | 0.97 |
| 399.47 | 1.58 | 1.58 |
| 400.46 | 0.97 | 0.97 |
| 389.44 | 0.30 | 0.30 |
| 327.36 | 1.90 | 1.90 |
| 514.63 | 1.90 | 1.90 |
| 340.36 | 1.65 | 1.65 |
| 418.48 | 1.18 | 1.18 |
| 315.35 | 1.76 | 1.76 |
| 372.41 | 0.15 | 0.15 |
| 344.35 | 0.23 | 0.23 |
| 348.38 | 0.05 | 0.05 |
| 331.35 | 0.73 | 0.73 |
| 435.53 | 1.22 | 1.22 |
| 323.37 | 0.07 | 0.07 |
| 261.35 | 2.67 | 2.67 |
| 496.61 | 3.01 | 3.01 |
| 309.35 | -0.32 | -0.32 |
| 527.84 | 5.24 | 5.24 |
| 403.46 | 0.31 | 0.31 |
| 417.46 | 1.72 | 1.72 |
| 385.45 | 1.52 | 1.52 |
| 367.43 | 0.18 | 0.18 |
| 427.49 | 0.41 | 0.41 |
| 389.43 | 1.17 | 1.17 |
| 405.44 | 0.27 | 0.27 |
| 420.52 | 1.34 | 1.34 |
| 400.46 | 0.97 | 0.97 |
| 444.54 | 1.44 | 1.44 |
| 421.50 | 0.74 | 0.74 |
| 343.40 | 2.54 | 2.54 |
| 531.69 | 2.93 | 2.93 |
| 363.44 | 0.94 | 0.94 |
| 460.58 | 2.22 | 2.22 |
| 297.34 | -0.46 | -0.46 |
| 421.50 | 0.62 | 0.62 |
| 263.36 | 2.92 | 2.92 |
| 420.52 | 1.34 | 1.34 |
| 341.39 | 2.29 | 2.29 |
| 399.47 | 1.58 | 1.58 |
| 417.49 | 0.62 | 0.62 |
| 309.35 | 0.06 | 0.06 |
| 405.44 | 0.27 | 0.27 |
| 334.36 | -0.43 | -0.43 |
| 429.50 | 1.59 | 1.59 |
| 428.47 | 0.81 | 0.81 |
| 337.40 | 0.55 | 0.55 |
| 515.62 | 1.29 | 1.29 |
| 403.46 | 0.31 | 0.31 |
| 497.58 | 0.87 | 0.87 |
| 390.42 | 0.57 | 0.57 |
| 428.47 | 0.97 | 0.97 |
| 373.43 | 2.17 | 2.17 |
| 498.57 | 1.43 | 1.43 |
| 400.46 | 0.97 | 0.97 |
| 280.35 | 1.60 | 1.60 |
| 404.45 | 0.88 | 0.88 |
| 357.43 | 2.93 | 2.93 |