Basic Information
ID: ALA4265323
Type: Binding
Description: Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured after 1 hr by Alexofluor 488-conjugated secondary antibody and Hoechst 33342 staining based assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4265323
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.37 | 1.80 | 1.80 |
| 388.45 | 0.93 | 0.93 |
| 362.41 | 0.54 | 0.54 |
| 348.38 | 0.05 | 0.05 |
| 443.53 | 1.19 | 1.19 |
| 341.39 | 2.15 | 2.15 |
| 358.38 | 0.62 | 0.62 |
| 442.50 | 0.61 | 0.61 |
| 325.39 | 0.31 | 0.31 |
| 301.32 | 1.37 | 1.37 |
| 380.47 | 0.09 | 0.09 |
| 417.49 | 0.80 | 0.80 |
| 351.43 | 1.03 | 1.03 |
| 514.63 | 1.90 | 1.90 |
| 418.48 | 1.36 | 1.36 |
| 405.52 | 2.11 | 2.11 |
| 345.38 | 1.39 | 1.39 |
| 460.51 | 0.99 | 0.99 |
| 341.39 | 2.29 | 2.29 |
| 337.40 | 0.55 | 0.55 |
| 347.40 | 0.16 | 0.16 |
| 459.53 | 0.42 | 0.42 |
| 444.51 | 1.75 | 1.75 |
| 327.36 | 1.90 | 1.90 |
| 514.63 | 1.90 | 1.90 |
| 340.36 | 1.65 | 1.65 |
| 315.35 | 1.76 | 1.76 |
| 372.41 | 0.15 | 0.15 |
| 344.35 | 0.23 | 0.23 |
| 331.35 | 0.73 | 0.73 |
| 435.53 | 1.22 | 1.22 |
| 323.37 | 0.07 | 0.07 |
| 261.35 | 2.67 | 2.67 |
| 367.43 | 0.18 | 0.18 |
| 427.49 | 0.41 | 0.41 |
| 444.54 | 1.44 | 1.44 |
| 343.40 | 2.54 | 2.54 |
| 531.69 | 2.93 | 2.93 |
| 363.44 | 0.94 | 0.94 |
| 460.58 | 2.22 | 2.22 |
| 341.39 | 2.29 | 2.29 |
| 399.47 | 1.58 | 1.58 |
| 309.35 | 0.06 | 0.06 |
| 334.36 | -0.43 | -0.43 |
| 515.62 | 1.29 | 1.29 |
| 497.58 | 0.87 | 0.87 |
| 428.47 | 0.97 | 0.97 |
| 373.43 | 2.17 | 2.17 |
| 498.57 | 1.43 | 1.43 |
| 357.43 | 2.93 | 2.93 |