ID: ALA4265503
Type: Binding
Description: Inhibition of recombinant human topoisomerase 2alpha assessed as decrease in relaxation of supercoiled pUC19 DNA at 100 uM after 30 mins by ethidium bromide staining based agarose gel electrophoresis relative to control
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4265503
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
421.42 | 4.22 | 4.22 |
406.45 | 4.32 | 4.32 |
436.47 | 4.42 | 4.42 |
410.86 | 4.97 | 4.97 |
485.34 | 5.08 | 5.08 |
419.49 | 4.38 | 4.38 |
421.42 | 4.22 | 4.22 |
394.41 | 4.45 | 4.45 |
445.31 | 5.62 | 5.62 |
376.42 | 4.31 | 4.31 |
445.31 | 5.62 | 5.62 |