Basic Information
ID: ALA4265765
Type: Binding
Description: Inhibition of ACAT in human J774A.1 cells assessed as reduction in esterified-cholesterol accumulation after 18 hrs in presence of 25-hydroxycholesterol by cholesterol E-test analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Acyl coenzyme A:cholesterol acyltransferase 1(ALA2782)
Document: ALA4261657
Inhibition of ACAT in human J774A.1 cells assessed as reduction in esterified-cholesterol accumulation after 18 hrs in presence of 25-hydroxycholesterol by cholesterol E-test analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4265765
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.68 | 7.43 | 7.43 |
| 481.71 | 7.43 | 7.43 |
| 466.69 | 8.54 | 8.54 |
| 478.70 | 8.39 | 8.39 |
| 508.73 | 6.20 | 6.20 |
| 496.75 | 5.89 | 5.89 |
| 519.79 | 4.79 | 4.79 |
| 503.72 | 4.32 | 4.32 |
| 522.76 | 6.55 | 6.55 |
| 479.69 | 5.16 | 5.16 |
| 458.63 | 7.55 | 7.55 |
| 494.71 | 5.81 | 5.81 |
| 450.65 | 7.61 | 7.61 |
| 539.20 | 4.06 | 4.06 |
| 521.78 | 6.28 | 6.28 |
| 504.71 | 3.72 | 3.72 |
| 538.83 | 7.01 | 7.01 |
| 481.67 | 4.82 | 4.82 |
| 523.75 | 5.94 | 5.94 |
| 422.59 | 7.14 | 7.14 |
| 480.68 | 5.42 | 5.42 |