Assay Report Card

Basic Information

ID: ALA4265804

Type: Binding

Description: Inhibition of ACAT in arterial homogenates isolated from 1% cholesterol fed New Zealand White rabbit unbound fraction adjusted IC50 for assessed as reduction in cholesteryl oleate formation incubated for 5 mins in presence of [14C]-oleoyl-CoA and BSA complex by TLC method

Organism: Oryctolagus cuniculus

Strain: New Zealand White

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
503.724.324.32
539.204.064.06
504.713.723.72