Basic Information
ID: ALA4266821
Type: Binding
Description: Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1 hr by TopCount scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4266821
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.79 | 5.30 | 5.30 |
| 381.81 | 5.90 | 5.90 |
| 378.28 | 5.54 | 5.54 |
| 374.89 | 6.97 | 6.97 |
| 329.81 | 4.70 | 4.70 |
| 343.84 | 4.89 | 4.89 |
| 333.24 | 5.95 | 5.95 |
| 367.78 | 5.71 | 5.71 |
| 328.82 | 5.31 | 5.31 |
| 334.23 | 5.35 | 5.35 |
| 344.82 | 4.29 | 4.29 |
| 366.79 | 6.32 | 6.32 |
| 368.67 | 6.00 | 6.00 |
| 342.80 | 5.03 | 5.03 |
| 348.85 | 6.45 | 6.45 |
| 328.20 | 5.29 | 5.29 |
| 363.36 | 5.07 | 5.07 |
| 362.37 | 5.67 | 5.67 |
| 446.68 | 6.48 | 6.48 |
| 382.70 | 6.19 | 6.19 |
| 360.76 | 6.26 | 6.26 |
| 377.39 | 5.26 | 5.26 |
| 435.77 | 6.85 | 6.85 |
| 354.90 | 6.60 | 6.60 |
| 449.80 | 6.92 | 6.92 |
| 375.78 | 5.84 | 5.84 |
| 367.68 | 6.61 | 6.61 |
| 334.23 | 5.35 | 5.35 |