ID: ALA4266822
Type: Binding
Description: Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after 1 hr by scintillation proximity assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4266822
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
382.79 | 5.30 | 5.30 |
381.81 | 5.90 | 5.90 |
378.28 | 5.54 | 5.54 |
402.22 | 6.37 | 6.37 |
416.25 | 6.55 | 6.55 |
416.25 | 6.55 | 6.55 |
380.82 | 6.63 | 6.63 |
392.86 | 6.18 | 6.18 |
329.81 | 4.70 | 4.70 |
435.78 | 6.73 | 6.73 |
343.84 | 4.89 | 4.89 |
416.25 | 6.55 | 6.55 |
367.78 | 5.71 | 5.71 |
328.82 | 5.31 | 5.31 |
334.23 | 5.35 | 5.35 |
344.82 | 4.29 | 4.29 |
366.79 | 6.32 | 6.32 |
348.85 | 6.45 | 6.45 |
341.75 | 4.26 | 4.26 |
416.25 | 6.55 | 6.55 |
362.37 | 5.67 | 5.67 |
446.68 | 6.48 | 6.48 |
416.25 | 6.55 | 6.55 |
382.70 | 6.19 | 6.19 |
360.76 | 6.26 | 6.26 |
377.39 | 5.26 | 5.26 |
435.77 | 6.85 | 6.85 |
416.25 | 6.55 | 6.55 |
375.78 | 5.84 | 5.84 |
326.74 | 4.56 | 4.56 |
378.68 | 5.46 | 5.46 |