Basic Information
ID: ALA4266822
Type: Binding
Description: Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after 1 hr by scintillation proximity assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Nuclear receptor ROR-gamma(ALA1741186)
Document: ALA4265886
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after 1 hr by scintillation proximity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4266822
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.79 | 5.30 | 5.30 |
| 381.81 | 5.90 | 5.90 |
| 378.28 | 5.54 | 5.54 |
| 402.22 | 6.37 | 6.37 |
| 416.25 | 6.55 | 6.55 |
| 416.25 | 6.55 | 6.55 |
| 380.82 | 6.63 | 6.63 |
| 392.86 | 6.18 | 6.18 |
| 329.81 | 4.70 | 4.70 |
| 435.78 | 6.73 | 6.73 |
| 343.84 | 4.89 | 4.89 |
| 416.25 | 6.55 | 6.55 |
| 367.78 | 5.71 | 5.71 |
| 328.82 | 5.31 | 5.31 |
| 334.23 | 5.35 | 5.35 |
| 344.82 | 4.29 | 4.29 |
| 366.79 | 6.32 | 6.32 |
| 348.85 | 6.45 | 6.45 |
| 341.75 | 4.26 | 4.26 |
| 416.25 | 6.55 | 6.55 |
| 362.37 | 5.67 | 5.67 |
| 446.68 | 6.48 | 6.48 |
| 416.25 | 6.55 | 6.55 |
| 382.70 | 6.19 | 6.19 |
| 360.76 | 6.26 | 6.26 |
| 377.39 | 5.26 | 5.26 |
| 435.77 | 6.85 | 6.85 |
| 416.25 | 6.55 | 6.55 |
| 375.78 | 5.84 | 5.84 |
| 326.74 | 4.56 | 4.56 |
| 378.68 | 5.46 | 5.46 |