Basic Information
ID: ALA4266823
Type: Binding
Description: Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at 1 uM after 1 hr by TopCount scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4266823
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.22 | 6.37 | 6.37 |
| 416.25 | 6.55 | 6.55 |
| 416.25 | 6.55 | 6.55 |
| 380.82 | 6.63 | 6.63 |
| 392.86 | 6.18 | 6.18 |
| 435.78 | 6.73 | 6.73 |
| 416.25 | 6.55 | 6.55 |
| 349.24 | 4.93 | 4.93 |
| 341.75 | 4.26 | 4.26 |
| 416.25 | 6.55 | 6.55 |
| 416.25 | 6.55 | 6.55 |
| 367.24 | 5.54 | 5.54 |
| 416.25 | 6.55 | 6.55 |
| 326.74 | 4.56 | 4.56 |
| 378.68 | 5.46 | 5.46 |
| 356.21 | 4.67 | 4.67 |