Basic Information
ID: ALA4266988
Type: Binding
Description: Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measured after 45 mins in presence of SAM by MTaseGlo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4266988
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.39 | 2.80 | 2.80 |
| 335.37 | 2.32 | 2.32 |
| 351.37 | 1.67 | 1.67 |
| 351.37 | 1.67 | 1.67 |
| 406.45 | 1.87 | 1.87 |
| 334.38 | 3.22 | 3.22 |
| 378.39 | 1.27 | 1.27 |
| 263.30 | 3.20 | 3.20 |
| 292.34 | 2.79 | 2.79 |
| 277.33 | 3.21 | 3.21 |
| 379.42 | 1.47 | 1.47 |
| 375.43 | 3.19 | 3.19 |
| 347.42 | 4.60 | 4.60 |