Basic Information
ID: ALA4267033
Type: Binding
Description: Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 peptide interaction preincubated for 1 hr followed by Biotin-Ahx-PMQS(pT)PLN-NH2 addition and measured after 1 hr by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PLK1(ALA3024)
Document: ALA4265898
Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 peptide interaction preincubated for 1 hr followed by Biotin-Ahx-PMQS(pT)PLN-NH2 addition and measured after 1 hr by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4267033
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 862.96 | 0.98 | 0.98 |
| 946.12 | 2.08 | 2.08 |
| 932.09 | 1.69 | 1.69 |
| 652.69 | 0.46 | 0.46 |
| 721.81 | 1.17 | 1.17 |
| 918.06 | 1.30 | 1.30 |