Assay Report Card

Basic Information

ID: ALA4267595

Type: Functional

Description: Desensitization of recombinant human GPR40 expressed in HEK293 cells assessed as reduction in TAK-875-induced intracellular calcium flux at 10 uM pretreated for 10 mins followed by compound washout and subsequent TAK-875 stimulation by calcium-5 dye based assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
342.394.684.68
356.424.994.99
362.815.025.02