Basic Information
ID: ALA4267723
Type: Binding
Description: Inhibition of recombinant human C-terminal His6-tagged GGPPS expressed in Escherichia coli BL21 at 1 to 10 uM using IPP and FPP as substrates pretreated for 15 mins followed by substrates addition and measured after 1 hr by colorimetric method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4267723
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.24 | 1.35 | 1.35 |
| 327.17 | -0.33 | -0.33 |
| 340.19 | 0.67 | 0.67 |
| 377.23 | 0.82 | 0.82 |
| 425.27 | 1.71 | 1.71 |
| 363.20 | 0.43 | 0.43 |
| 439.30 | 2.10 | 2.10 |
| 326.18 | 0.19 | 0.19 |
| 299.12 | -1.11 | -1.11 |
| 363.20 | 0.43 | 0.43 |
| 363.20 | 0.43 | 0.43 |
| 313.14 | -0.72 | -0.72 |
| 376.24 | 1.34 | 1.34 |
| 363.20 | 0.43 | 0.43 |
| 377.23 | 0.82 | 0.82 |
| 349.18 | 0.04 | 0.04 |
| 349.18 | 0.04 | 0.04 |
| 340.19 | 0.61 | 0.61 |
| 376.24 | 1.34 | 1.34 |