Basic Information
ID: ALA4268221
Type: Binding
Description: Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by ion exchange filter paper method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4268221
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 304.35 | 3.85 | 3.85 |
| 387.49 | 4.84 | 4.84 |
| 389.46 | 3.68 | 3.68 |
| 403.49 | 3.99 | 3.99 |
| 516.65 | 5.66 | 5.66 |
| 514.03 | 5.07 | 5.07 |
| 433.51 | 4.67 | 4.67 |
| 387.49 | 4.84 | 4.84 |
| 463.54 | 4.60 | 4.60 |
| 449.51 | 4.29 | 4.29 |
| 532.65 | 4.82 | 4.82 |
| 527.03 | 4.63 | 4.63 |
| 576.53 | 3.85 | 3.85 |
| 462.55 | 5.35 | 5.35 |
| 561.69 | 3.91 | 3.91 |
| 500.00 | 4.68 | 4.68 |
| 576.53 | 3.85 | 3.85 |
| 516.65 | 5.66 | 5.66 |
| 518.62 | 4.51 | 4.51 |
| 545.69 | 4.73 | 4.73 |
| 402.50 | 3.60 | 3.60 |
| 491.59 | 5.38 | 5.38 |
| 485.97 | 4.29 | 4.29 |
| 527.03 | 4.63 | 4.63 |
| 514.03 | 5.07 | 5.07 |
| 531.66 | 4.42 | 4.42 |
| 561.69 | 3.91 | 3.91 |
| 463.54 | 4.68 | 4.68 |
| 477.57 | 4.99 | 4.99 |