Basic Information
ID: ALA4268298
Type: Binding
Description: Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in flufenamic acid-evoked increase in intracellular calcium level at 10 uM measured for 180 secs with 1 sec interval by Fluo4-AM dye-based fluorescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily A member 1(ALA6007)
Document: ALA4265944
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in flufenamic acid-evoked increase in intracellular calcium level at 10 uM measured for 180 secs with 1 sec interval by Fluo4-AM dye-based fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4268298
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 355.40 | 1.20 | 1.20 |
| 399.45 | 1.38 | 1.38 |
| 455.56 | 2.94 | 2.94 |
| 385.42 | 1.20 | 1.20 |
| 485.59 | 3.03 | 3.03 |
| 413.48 | 1.77 | 1.77 |
| 471.56 | 2.64 | 2.64 |