Basic Information
ID: ALA4268493
Type: Binding
Description: Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholine-induced vasorelaxation by pressure myographic method
Format: BAO_0000357
Organism: Rattus norvegicus
Strain: Wistar
Target: Phosphodiesterase 5A(ALA4567)
Document: ALA4265950
Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholine-induced vasorelaxation by pressure myographic method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4268493
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.41 | 2.21 | 2.21 |
| 379.49 | 4.09 | 4.09 |
| 365.46 | 2.85 | 2.85 |
| 379.49 | 4.09 | 4.09 |
| 363.42 | 2.64 | 2.64 |
| 363.42 | 3.62 | 3.62 |
| 379.49 | 3.11 | 3.11 |
| 363.42 | 3.62 | 3.62 |
| 430.33 | 3.31 | 3.31 |
| 349.39 | 3.37 | 3.37 |