Assay Report Card

Basic Information

ID: ALA4268535

Type: Binding

Description: Inhibition of HDAC in synchronized trophozoite stage Plasmodium falciparum 3D7 infected in human erythrocytes assessed as increase in acetylated H4 level at 5 times IC50 after 3 hrs by Western blot analysis relative to control

Organism: Plasmodium falciparum 3D7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
264.322.472.47
452.562.962.96
460.533.463.46
437.543.513.51
445.524.014.01
426.522.432.43
459.554.054.05
423.513.213.21
437.543.513.51
426.522.432.43
411.502.982.98
451.574.024.02