Basic Information
ID: ALA4268535
Type: Binding
Description: Inhibition of HDAC in synchronized trophozoite stage Plasmodium falciparum 3D7 infected in human erythrocytes assessed as increase in acetylated H4 level at 5 times IC50 after 3 hrs by Western blot analysis relative to control
Format: BAO_0000219
Organism: Plasmodium falciparum 3D7
Target: Histone deacetylase(ALA1293190)
Document: ALA4265952
Inhibition of HDAC in synchronized trophozoite stage Plasmodium falciparum 3D7 infected in human erythrocytes assessed as increase in acetylated H4 level at 5 times IC50 after 3 hrs by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4268535
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 452.56 | 2.96 | 2.96 |
| 460.53 | 3.46 | 3.46 |
| 437.54 | 3.51 | 3.51 |
| 445.52 | 4.01 | 4.01 |
| 426.52 | 2.43 | 2.43 |
| 459.55 | 4.05 | 4.05 |
| 423.51 | 3.21 | 3.21 |
| 437.54 | 3.51 | 3.51 |
| 426.52 | 2.43 | 2.43 |
| 411.50 | 2.98 | 2.98 |
| 451.57 | 4.02 | 4.02 |